How is prothrombin gene mutation treated?

How is prothrombin gene mutation treated?

Can the prothrombin gene mutation be treated? No treatment can prevent the prothrombin gene mutation or make it go away. The goal of treatment is to prevent blood clots (see next question and page 7). If you have had a blood clot, you may be treated with medications called anticoagulants.

What is prothrombin G20210A?

Prothrombin G20210A is a genetic condition that increases the risk of blood clots including from deep vein thrombosis, and of pulmonary embolism. One copy of the mutation increases the risk of a blood clot from 1 in 1,000 per year to 2.5 in 1,000.

How do you test for prothrombin gene mutation?

Prothrombin testing is done by taking a blood sample, and using a genetic test to look at the prothrombin gene. The DNA is isolated from blood cells and the prothrombin gene is examined to see if there is a mutation in the DNA code.

How common is prothrombin 20210 mutation?

The mutation is uncommon in African Americans (approximately 0.5%) and is rare in Asians, Africans, and Native Americans. The homozygous form is considered uncommon, with an expected occurrence of approximately 1 in 10 000 individuals. The prothrombin 20210 mutation is equally as common in men and in women.

How rare is factor2?

Factor II deficiency is a rare, inherited or acquired bleeding disorder with an estimated incidence of one case per 2 million population. Accordingly, they usually have either little normal prothrombin or a near-normal output of dysfunctional prothrombin.

Can thrombophilia be cured?

You can have thrombophilia and never develop a blood clot or need treatment. In some cases, your doctor may recommend long-term use of blood thinners, which will require periodic blood testing. Thrombophilia can be successfully managed.

Can you have a baby with thrombophilia?

In general, women with thrombophilia do not have more pregnancies with complications, but late pregnancy loss in the first or later in the second trimester, placental abruption, and incomplete fetal development are the most frequent. Also, thrombophilia may be clots implicated in preeclampsia.

Is thrombophilia a disability?

People who have deep vein thrombosis are at risk for pulmonary embolism or stroke, both life-threatening conditions, and are sometimes advised not to work. Depending on their particular condition, they may qualify for disability benefits from Social Security.

What is factor 10 called?

Factor X (FX) circulates as a vitamin K–dependent serine protease that is converted to the active form at the point of convergence of the intrinsic and extrinsic coagulation pathways.

Does thrombophilia cause miscarriage?

Blood tests to show your risk of miscarriage have become more common. The tests show if you have a condition called “thrombophilia.” This condition can increase blood clots. It may increase the risk of a miscarriage or other problems during pregnancy.