What are the limitations of conventional drug delivery?

What are the limitations of conventional drug delivery?

Conventional drug delivery systems contain numerous limitations such as limited targeting, low therapeutic indices, poor water solubility, and the induction of drug resistances.

What are the advantages of novel drug delivery method over conventional drug delivery method?

Reduction in the number and frequency of doses required to maintain the desired therapeutic response. Reduce the total amount of drug administered over the period of drug treatment. Reduced blood level oscillation characteristic of multiple dosing of conventional dosage forms.

Why do we need drug delivery systems?

Drug delivery systems are engineered technologies for the targeted delivery and/or controlled release of therapeutic agents. Drugs have long been used to improve health and extend lives. Drug delivery systems control the rate at which a drug is released and the location in the body where it is released.

Which is the advantage of newer drug delivery system?

Advantages of advanced drug delivery systems over traditional systems are the ability to deliver a drug more selectively to a specific site; easier, more accurate, less frequent dosing; decreased variability in systemic drug concentrations; absorption that is more consistent with the site and mechanism of action; and …

What are nasal drug delivery systems?

Drugs are cleared rapidly from the nasal cavity after intranasal administration, resulting in rapid systemic drug absorption. These drug delivery systems have the ability to control the rate of drug clearance from the nasal cavity as well as protect the drug from enzymatic degradation in nasal secretions.

Which drug delivery has longest duration of action?

The present limit on duration of rate-controlled oral products is currently set by the transit of solid dosage forms through the gastrointestinal tract: the longest of the oral delivery system products has a delivery time of 18 h [7].

How are drugs intranasally administered?

They are sprayed into the nostrils, usually to produce a local effect directly inside the nose. Some nasal sprays are used to administer medicine that acts on other parts of the body. In these cases the medicine is taken into the bloodstream from the lining of the nose, which has many blood vessels.