What causes an increase in monocytes in the blood?

What causes an increase in monocytes in the blood?

Increased number of monocytes. An increased number of monocytes in the blood (monocytosis) occurs in response to chronic infections, in autoimmune disorders, in blood disorders, and in certain cancers.

When do you have a change in monocyte number?

However, people may have symptoms of the disorder that caused the change in monocyte number. Diagnosis is by blood testing (complete blood count) done when a person has signs or symptoms of an infection or autoimmune disorder.

What causes an increase in lymphocyte count in tuberculosis?

The lymphocyte count may also be increased in chronic bacterial infections. Tuberculosis infection is accompanied by an increase in lymphocytes and monocytes.

What makes up the differential in a blood count?

The differential usually includes neutrophils, bands, eosinophils, monocytes and lymphocytes.

What kind of inflammation has a high monocyte count?

Monocytosis is defined by an absolute monocyte count of greater than 500/µL and usually occurs in the setting of chronic inflammation resulting from infections like tuberculosis, syphilis, or subacute bacterial endocarditis, autoimmune or granulomatous disease, and sarcoidosis.

Can a bacterial infection cause an increase in white count?

Viral vs. bacterial with help of the CBC. Tuberculosis infection is accompanied by an increase in lymphocytes and monocytes. Since many infections are localized, changes will not be seen in the CBC. A variety of non-infectious inflammatory conditions, other than infection, can cause increases in the white count, including leukemia and trauma.

What does bone marrow culture do for monocyte count?

Disorders of monocyte numbers are described on page 234. Bone marrow will confirm the presence or absence of neutrophil precursors, maturation arrest of the neutrophil series, marrow replacement, or infiltration. Culture of bone marrow will assess the colony-forming ability of the granulocytes.

What is the normal relative monocyte count in an adult?

The normal relative monocyte count in the adult varies between 1 and 9% of the circulating leukocyte population (Cassileth, 1972; Wintrobe, 1967 ). The relative monocyte count is significantly elevated when it exceeds 10%. In children, the average relative count is 9%.