What is Enteropathica?

What is Enteropathica?

What is Enteropathica?

Acrodermatitis enteropathica (AE) is a disorder of zinc metabolism that occurs in one of three forms: an inborn (congenital) form and two acquired forms. The inborn form of AE is a rare genetic disorder characterized by intestinal abnormalities that lead to the inability to absorb zinc from the intestine.

Can adults get acrodermatitis?

Acrodermatitis enteropathica (AE) is a rare dermatitis secondary to zinc deficiency most commonly seen as an inherited disease in infants. In the last decade, increased number of reports have been published on the acquired form that presents in adulthood.

How do you get rid of acrodermatitis?

Treatment of acrodermatitis enteropathica requires lifelong zinc supplementation. Typically, 1-3 mg/kg of zinc gluconate or sulfate is administered orally each day. Clinical improvement occurs prior to any significant change in the plasma zinc levels, usually within days to weeks of initiating treatment.

How common is acrodermatitis?

While the overall incidence of childhood acrodermatitis is unknown, it’s considered a relatively mild condition. However, several acrodermatitis epidemics have been reported over the years. Experts believe these epidemics were caused by viral infections , which can trigger acrodermatitis in children.

What is the cause of zinc deficiency?

Zinc deficiency affects the skin and gastrointestinal tract; brain and central nervous system, immune, skeletal, and reproductive systems. Zinc deficiency in humans is caused by reduced dietary intake, inadequate absorption, increased loss, or increased body system use. The most common cause is reduced dietary intake.

Is Acrodermatitis contagious?

Acrodermatitis causes itchy red or purple blisters to form on the body. Children may also develop a bloated abdomen, a fever, and swollen, sore lymph nodes. Although acrodermatitis itself isn’t contagious, the viruses that cause it are contagious.

How does Acrodermatitis affect the skin?

It is characterized by inflammation of the skin (dermatitis) around bodily openings (periorificial) and the tips of fingers and toes (acral), hair loss (alopecia), and diarrhea. It can also be related to deficiency of zinc due to other, i.e. congenital causes.

How do you treat Gianotti crosti syndrome?

Gianotti-Crosti syndrome (GCS) is a benign self-limited condition that requires no treatment. Topical steroids are generally not effective, although anecdotal responses have been reported. Systemic treatment with antihistamines has been moderately helpful in relieving pruritus.

How do I know if I need zinc?

Weight loss, problems with wound healing, decreased ability to taste food, and lower alertness levels can also occur. Many of these symptoms can be signs of problems other than zinc deficiency. If you have these symptoms, your doctor can help determine whether you might have a zinc deficiency.

How do you treat Gianotti-crosti syndrome?