Why is bismuth used in quadruple therapy?

Why is bismuth used in quadruple therapy?

In travelers diarrhea bismuth was shown to function as a topical antimicrobial thus linking its use as an anti-infective to it subsequent use for treatment of H. pylori-related peptic ulcer disease 5-7. The most widely used forms of bismuth in use for gastroenterology at the time of the discovery of H.

How do you take bismuth quadruple therapy?

Completely chew and swallow 2 bismuth tablets. Swallow the metronidazole tablets and tetracycline capsules with a full glass (8 ounces) of water. Do not chew, crush, or break the metronidazole tablets and tetracycline capsules. Take this medicine with meals and at bedtime.

How long is bismuth quadruple therapy?

Background: Bismuth-containing quadruple therapy given twice a day for 14 days has been shown to be an excellent first-line H. pylori eradication therapy. Aim: To compare the efficacy and tolerability of twice-a-day bismuth-containing quadruple H.

Can I take bismuth with food?

Take bismuth, metronidazole, and tetracycline at least 1 hour before or 2 hours after you eat or drink foods that contain calcium, such as dairy products and calcium-fortified juices and foods. Continue to take this medication even if you feel well. Do not stop taking it without talking to your doctor.

Is bismuth an antibiotic?

Bismuth colloids have an antibacterial action, which is relevant for the treatment of infectious diarrhea and peptic ulcers (e.g., Helicobacter pylori). The salicylate component of bismuth subsalicylate may exert intestinal antiinflammatory and antisecretory actions.

Should bismuth be taken with food?

Bismuth subsalicylate comes as a liquid, tablet, or chewable tablet to be taken by mouth, with or without food. Follow the directions on the package carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take bismuth subsalicylate exactly as directed.

Can u OD on Pepto-Bismol?

In case of overdose Symptoms of a Pepto-Bismol overdose can include: ringing in your ears. loss of hearing. extreme drowsiness.

Can I take bismuth on empty stomach?