What classification is Methergine?

What classification is Methergine?

Methylergonovine belongs to a class of drugs known as ergot alkaloids. It works by increasing the rate and strength of contractions and the stiffness of the uterus muscles.

What kind of medication is Methylergonovine?

Methylergonovine is in a group of drugs called ergot alkaloids. It affects the smooth muscle of a woman’s uterus, improving the muscle tone as well as the strength and timing of uterine contractions. Methylergonovine is used just after a baby is born, to help deliver the placenta (also called the “afterbirth”).

What do the adverse effects of Methylergonovine Methergine include?

The most common adverse reaction is hypertension associated in several cases with seizure and/or headache. Hypotension has also been reported. Abdominal pain (caused by uterine contractions), nausea and vomiting have occurred occasionally.

How is Methergine taken?

Methylergonovine injection is given into a muscle or into a vein through an IV. You will receive this injection while you are in the delivery room and for a short time after your baby is born, if needed. Methylergonovine oral is a tablet taken by mouth 3 or 4 times daily for up to 1 week after your baby is born.

How long does it take for Methergine to start working?

The onset of action after I.V. administration is immediate; after I.M. administration, 2-5 minutes, and after oral administration, 5-10 minutes.

How long does Methergine stay in your system?

The plasma level decline was biphasic with a mean elimination half-life of 3.39 hours (range 1.5 to 12.7 hours). A delayed gastrointestinal absorption (Tmax about 3 hours) of Methergine tablet might be observed in postpartum women during continuous treatment with this oxytocic agent.

How long does Methergine last?

What is the purpose of Methergine?

Methylergonovine belongs to a class of drugs called ergot alkaloids. Methylergonovine is used to prevent or treat bleeding from the uterus that can happen after childbirth or an abortion.

What is the action of Methergine?

Methergine (methylergonovine maleate) acts directly on the smooth muscle of the uterus and increases the tone, rate, and amplitude of rhythmic contractions. Thus, it induces a rapid and sustained tetanic uterotonic effect which shortens the third stage of labor and reduces blood loss.