What are the symptoms of central pontine myelinolysis?

What are the symptoms of central pontine myelinolysis?

The initial symptoms of myelinolysis, which begin to appear 2 to 3 days after hyponatremia is corrected, include a depressed level of awareness, difficulty speaking (dysarthria or mutism), and difficulty swallowing (dysphagia).

Is central pontine myelinolysis rare?

Central pontine and extrapontine myelinolysis (CPEM) is rare. The occurence of CPM may be associated with hyponatremia, a rapid rise in serum sodium concentrations, postoperatively increased plasma osmolality, and the duration of the operation.

How common is central pontine myelinolysis?

Central pontine myelinolysis (CPM) is a demyelinating disease of the pons and is associated with a rapid correction of hyponatremia172 or large fluid shifts occurring during transplant. It is one of the most serious neurological complications occurring in liver transplantation, but the incidence is now less than 1%.

Is central pontine myelinolysis fatal?

Central pontine myelinolysis (CPM), a potentially fatal and debilitating neurological condition, was first described in 1959 in a study on alcoholic and malnourished patients. It is a condition most frequently related to rapid correction of hyponatremia.

How is central pontine myelinolysis diagnosed?

Diagnosing central pontine myelinolysis To help diagnose CPM, your doctor will run blood tests to measure your sodium levels. An MRI of your head can show any damage to your brain stem. You may also take a brainstem auditory evoked response (BAER) test.

What happens if pons are damaged?

In fact, destruction of the midbrain, pons, or medulla oblongata causes “brain death”, and the unfortunate victim of the injury cannot survive. And while damage to brain stem can cause death, even an injury that does not cause death, can cause significant brain stem injury symptoms.

Is central pontine Myelinolysis reversible?

Similarly to prior CPM case reports, this patient significantly improved following reinduction of hyponatremia, methylprednisolone, and/or plasmapharesis. This report demonstrates that CPM is potentially reversible when quickly recognized and therapeutic interventions are initiated rapidly.

Is pontine Myelinolysis reversible?

Can central pontine Myelinolysis be reversed?

The destruction of myelin is generally not spontaneous. CPM usually happens as a result of another illness or medical condition. The disorder can’t be cured, but its symptoms can be treated. CPM is one of the two types of osmotic demyelination syndrome (ODS).

What is the function of pons in hindbrain?

The pons relays sensory information between the cerebrum and cerebellum. Functions under the control of the cerebellum include fine motor coordination and control, balance, equilibrium, muscle tone, fine motor coordination, and a sense of body position.

What is the main function of pons?

The pons, while involved in the regulation of functions carried out by the cranial nerves it houses, works together with the medulla oblongata to serve an especially critical role in generating the respiratory rhythm of breathing. Active functioning of the pons may also be fundamental to rapid eye movement (REM) sleep.

What is the role of the pons?

The pons is the largest part of the brainstem, located above the medulla and below the midbrain. It is a group of nerves that function as a connection between the cerebrum and cerebellum (pons is Latin for bridge).

What does the right pons control?

The pons contains nuclei that relay signals from the forebrain to the cerebellum, along with nuclei that deal primarily with sleep, respiration, swallowing, bladder control, hearing, equilibrium, taste, eye movement, facial expressions, facial sensation, and posture.